Expert Rev Clin Pharmacol. 2012;5(3):319-336. Finally, a recent study suggested that although prasugrel significantly reduces thrombotic events in patients with ACS undergoing PCI because of its ...

There are controversial data concerning prasugrel resistance, and there is a need for larger studies to confirm prasugrel resistance. IPA: Inhibition of platelet aggregation; iv.: Intravenous.

PharmaCenter Bonn & Pharmaceutical Institute, Pharmaceutical & Medicinal Chemistry, University of Bonn, An der Immenburg 4, 53121 Bonn, Germany Collaborative Research Center (CRC/SFB 1328), Department ...

Figure. Hazard ratio for efficacy (95% confidence interval) evaluated as the composite end point of cardiovascular death, myocardial infarction, or stroke, in the Clopidogrel in Unstable Angina to ...

Although true bifurcation lesions are associated with a high risk of procedural complications, the differential prognostic implications of percutaneous coronary intervention for true bifurcations ...

Calcium homeostasis plays an essential role in maintaining excitation–contraction coupling (ECC) in cardiomyocytes, including calcium release, recapture, and storage. Disruption of calcium homeostasis ...

Hematemesis is the medical term used to describe vomiting blood. The blood can be bright red, dark red, black, or dark brown, or resemble coffee grounds. It is caused by internal gastrointestinal (GI) ...

BHF Centre for Cardiovascular Science, University of Edinburgh, Edinburgh, UK Correspondence to Dr Andrew R Chapman, BHF Centre for Cardiovascular Science, Chancellors Building, University of ...

The ULTIMATE-DAPT (One-Month Ticagrelor Monotherapy After PCI in Acute Coronary Syndromes) trial data demonstrated that, in patients with acute coronary syndrome who underwent percutaneous coronary ...

In this study, researchers evaluated the effects of P2Y12 inhibitors (clopidogrel, prasugrel, or ticagrelor) compared to aspirin in patients with established coronary artery disease. The study ...

Background: ST-segment elevation myocardial infarction (STEMI) patients are at a high residual risk of major adverse cardiovascular events (MACEs) after revascularization. Risk factors modify ...

Aims Clopidogrel is the most commonly prescribed thienopyridine as part of dual anti-platelet therapy for the treatment of ...