Here I discuss recent advances in the study of endoplasmic reticulum stress as one mechanism that links immune response with nutrient sensing in the pathogenesis of atherosclerosis and its ...

A detailed quantitative model of signaling by IRE1 sheds light on the mechanism of its activation by endoplasmic reticulum stress and addresses a long-standing controversy in the field. In ...

The peripheral endoplasmic reticulum (ER) forms a continuous, dynamic network of tubules that plays an important role in protein transport and quality control, cellular signaling, and stress response.

New research details the subcellular structures in neurons that enable signals to be transmitted from where they are received at specific sites on dendrites to the decision-making cell body located ...

Researchers from Stanford University and LMU have uncovered how cells renew their endoplasmic reticulum’s protein factories. One of the essential functions of life is the cell’s synthesis of ...

The new research finds that the endoplasmic reticulum and the plasma membrane form contact sites where specialized molecules control the release of calcium, which regulates the signals sent along the ...