Neurological diseases are highly heterogeneous; however, they share a common pathogenesis, that is, the aberrant accumulation of misfolded/unfolded proteins within the endoplasmic reticulum (ER).

Current research highlights the need for safer and more effective therapies for APAP-induced liver injury, especially those that target oxidative and endoplasmic reticulum (ER) stress pathways. This ...

This is a python script tool to automatically find active TCPInterface servers, list them and select the servers you want to add to Reticulum config automatically ...

SARCOTUBULAR, fragments prepared from homogenates of skeletal muscle are able to sequester vigorously calcium ions if ATP is available, and they show the activity of Mg-ATPase and Ca-ATPase which ...

New research details the subcellular structures in neurons that enable signals to be transmitted from where they are received at specific sites on dendrites to the decision-making cell body located ...

Insulin resistance precedes and predicts the onset of type 2 diabetes mellitus (DM2), a chronic disease that causes high ...

Results As well as inducing transcriptional modules implicated in antimicrobial responses, IL22 also coordinated an endoplasmic reticulum (ER) stress response transcriptional programme in colonic ...

The Iowa Farm Sanctuary has released more information about how Phill the water buffalo likely died. Late last week Phill was ...

A new role of calcium in the development of muscles has been reported by two RIKEN biologists.

Insulin resistance precedes and predicts the onset of type 2 diabetes mellitus (DM2), a chronic disease that causes high morbidity and mortality worldwide. In affected people, insulin is unable to ...

The intestinal epithelium is a highly dynamic barrier that regulates digestion, absorption, immune responses, and ...

A new study finds that cannabidiol (CBD) may effectively combat colorectal cancer (CRC), showing antitumor effects across ...