Why did you do this work? Children’s Intensive Care (CICU) is a complex and challenging environment where nuanced and critical care is delivered to each patient. As trainees rotate through this unit ...

SMA is a motor neuron disease characterised by generalised muscle atrophy and weakness. It is caused by the dysfunction and eventual death of motor neurons, due to deletions of SMN1 in 95% of patients ...

Background and Objectives Prolonged neonatal jaundice is defined as jaundice persisting in a term neonate at 14 days and a preterm neonate at 21 days of age. Prolonged neonatal jaundice is most ...

Aims • Raise awareness of plastic pollution and its dangers to marine animals and potentially humans. • Education of children in schools • Litter-picking Methods In 2017 WASUP was founded. A working ...

Aim There is an increased use of Hormonal Contraceptives (HCs) in female adolescents, during a period of growth, development and hormonal changes.1 2 Due to the limited long-term safety data available ...

Background Mental health problems are prevalent in children and young people (CYP). Children with neurodevelopmental disorders such as ASD have co-morbid mental health difficulties which add to the ...

Objective The β2-agonists such as salbutamol are the mainstay of asthma management. Pharmacokinetic–pharmacodynamic (PKPD) models to guide paediatric dosing are lacking. We explored the relationship ...

Objectives Asthma is the most common chronic condition in children, affecting 2–3 in every primary school class.1 Asthma disproportionately affects children living in poverty due to air pollution, ...

Objectives Hand dominance usually develops in children around 18 months old, while earlier hand preference may indicate cerebral palsy.1 Hand preference in humans is thought to be related to the ...

Introduction More than half of all drugs are still prescribed off-label to children. To support off-label dosing, pharmacokinetic (PK) data are needed. Physiologically-based pharmacokinetic (PBPK) ...

What did you do? We conducted an evaluation of families’ experiences with community and specialist swimming lessons amongst children with disabilities accessing a specialist swimming program. Sparkle ...

Methods We used novel linkage between health and education records from the Education and Child Health Insights from Linked Data (ECHILD) database to develop a whole-country cohort of children ...