1 Departments of Infectious Diseases (KLW), Public Health and Preventive Medicine (DC, KLW, DA), Ophthalmology (EBS, JTR, KLW, CDV), and Rheumatology (JTR), Oregon Health & Science University, ...

Objectives To determine whether the process of ubiquitination and/or activity of the 26S proteasome are involved in the induction of osteoarthritis (OA). Methods Bovine cartilage resorption assays, ...

Background From 2009 Abatacept (ABA) – a new generation biological DMARD was approved in Russia. ABA selectively modulates T-cell activation, which seems to play the key role in the pathogenesys of ...

The most common form of facial paralysis is idiopathic—that is, Bell's palsy. Sjögren's syndrome (SS), a chronic inflammatory disorder characterised by lymphocytic infiltration of exocrine glands ...

Background The prevalence of psoriatic arthritis (PsA) is considered equal in male and female patients but recent studies in cohorts of PsA it has been observed that women are more dominant in sex ...

Background Biologics, in particular monoclonal antibodies (mAbs), transformed treatment of autoimmune diseases such as rheumatoid arthritis (RA) by selectively targeting pathogenesis and modifying ...

3 Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA 4 US Department of Veterans Affairs Medical Center, Cincinnati, Ohio, USA 5 Department of Clinical Pharmacology, Oklahoma Medical ...

Objectives We aimed to cluster patients with rheumatoid arthritis (RA) based on comorbidities and then examine the association between these clusters and RA disease activity and mortality. Methods In ...

Academic Medical Centre, University of Amsterdam, Department of Medical Microbiology, the Netherlands Dr J H Ringrose, Department of Medical Microbiology, Academic Medical Centre, AMC L1–160, PO Box ...

3 Department of Medical Biochemistry and Microbiology, Uppsala University, Uppsala, Sweden 4 Department of Biomedical Sciences and Veterinary Public Health, Swedish University of Agricultural Sciences ...