Naltrexone is used as an off-label treatment in low doses for several chronic immune-modulated disorders in many countries. Although only small-scale clinical trials have been performed, these suggest ...

Katie Francine Lee, Rathnayaka Mudiyanselage Kalpanee Dhanushika Gunasingha, Jonathan Keung, Benjamin Potter, Ross Puffer, Michele Gage ...

Pulmonary arterial hypertension (PAH) is a progressive disease of the pulmonary vasculature that results in precapillary pulmonary hypertension. PAH is caused by a group of clinical conditions ...

This case series documents three patients referred to the Intensive Dietary Management clinic in Toronto, Canada, for insulin-dependent type 2 diabetes. It demonstrates the effectiveness of ...

We report a case of an antenatal patient who was referred with an anomaly scan of a fetus suspected to have skeletal dysplasia associated with a hypoplastic heart. Genetic counselling was provided, ...

Haemochromatosis is marked by excessive iron accumulation leading to damage to various organs. Although haemochromatosis dates to 1865, diagnosing the condition remains challenging due to its ...

Extreme heat impacts on child health and well-being due to immature thermoregulation, less sweating and a high surface-to-body mass ratio that make them more vulnerable to heat-related illness. Severe ...

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Solitary, benign retroperitoneal neurofibromas are exceedingly rare. Our case report highlights a man who presented with left-sided abdominal pain and left lower extremity numbness and weakness. On ...

Oxalate nephropathy is a rare condition and may be overlooked due to lack of recognition and understanding of triggers. An 81-year-old man was sent to nephrologist because of significantly increased ...

Drug abuse by inhalation of volatile household product substances is uncommon, however, it can have devastating consequences. This case report describes the fatal outcome of deodorant inhalation by a ...

Systemic capillary leak syndrome (SCLS), also known as Clarkson’s disease, is a rare disorder of unknown aetiology. Since SCLS was first described in 1960, fewer than 500 cases have been reported.