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Department of Electrical, Computer, and Biomedical Engineering, Toronto Metropolitan University, Toronto, Ontario M5B 2K3, Canada Li Ka Shing Knowledge Institute, Unity Health Toronto (St. Michael’s ...

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在构建 NAFLD 球体模型后，研究人员发现，球体在培养过程中逐渐形成了正常肝细胞的形态。FFA 刺激会抑制球体活力，而褐藻糖胶处理后，球体活力明显恢复。同样，FFA 会使球体中 TG 含量升高，褐藻糖胶则能让它降下来，油红 O 染色也再次证实了褐藻糖胶可以抑制球体中的脂质积累。这些结果充分表明，褐藻糖胶就像一位 “减脂小能手”，能够有效改善 FFA 诱导的脂质积累问题。