The life cycle of viruses varies greatly depending on the type and class of virus, but they follow the same basic stages of viral replication, i.e., adsorption, entry, uncoating, replication, assembly ...

uncoating of viral particles; and degradation of engulfed apoptotic cells. One of the cellular detectors of dsRNA is TLR3 (see the figure, part,a). dsRNA binds Toll-like receptor 3 (TLR3), which ...

Adeno-associated viruses (AAV) have emerged as the lead vector in clinical trials and form the basis for several approved gene therapies for human diseases, mainly owing to their ability to sustain ...

Helicases are dynamic enzymes that play essential roles in DNA and RNA metabolism, transcription, repair, and recombination and are often dysregulated in human diseases. In addition, helicases are ...

I Departamento de Microbiologia e Parasitologia, Universidade Federal de Santa Maria, Santa Maria, RS, Brasil II Departamento de Medicina Veterinária Preventiva. Universidade Federal de Santa Maria, ...