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生物通
5 天
靶向 ERO1A:小分子抑制剂开启三阴性乳腺癌治疗新征程
在肿瘤的世界里,癌细胞就像一群狡猾又顽强的 “侵略者”,它们能在恶劣的环境中不断适应、发展壮大。肿瘤内部常常处于缺氧、营养匮乏的状态,还伴随着各种致癌突变,这就像是给癌细胞设置了重重 “障碍关卡”。但癌细胞却有自己的 “生存秘籍”—— 激活未折叠蛋白反应(Unfolded Protein Response,UPR),以此来维持内质网(Endoplasmic ...
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