Study reveals how the JAK inhibitor lowers ACE2 expression and viral entry in individuals with a genetic risk variant linked to autoimmune diseases. Study: Tofacitinib Mitigates the Increased SARS ...

Janus kinase (JAK) inhibitors are a class of drugs that are being widely used to treat chronic inflammatory diseases and immune-mediated diseases. “Tofacitinib’s ability to reduce ACE2 ...