Aneuploidy is frequent in cancer, but in vitro it triggers multiple cellular stresses and often delays proliferation. Through ...

Amid increased scrutiny of price action in the SME segment by regulators and investors alike, a looks at their fundamentals in a three-part series. Part-1 examines sharp decline in operating cash flow ...

Non-invasive prenatal testing (NIPT) is at the forefront of prenatal screening. Current uses for NIPT include fetal sex determination and screening for chromosomal disorders such as trisomy 21 (Down ...

Objective Although counting of circulating tumour cells (CTC) has attracted a broad interest as potential markers of tumour progression and treatment response, the lack of functional characterisation ...

Background PARP inhibitors (PARPi) have been licensed for the maintenance therapy of patients with metastatic pancreatic cancer carrying pathogenic germline BRCA1/2 mutations. However, mutations in ...

Our findings propose high CDC20 expression as a molecular feature associated with the sensitivity to SAC inhibition therapy and as a potential aneuploidy-induced cellular vulnerability. High CDC20 ...

It is a big day for animated films at the Oscars, with Chris Sanders’ The Wild Robot earning three nominations and Gints Zilbalodis’ Flow picking up two nominations at the 97th annual Academy ...

Gints Zilbalodis’ Flow, the animated film that had its world premiere at the Cannes Film Festival, has earned Latvia its first Academy Award nominations. The film landed Best Animated Feature ...

The contenders for the 97th Academy Awards ceremony have been unveiled, kicking off the final leg of the race for the international honor. By Georg Szalai Global Business Editor ...

Samples were run by flow cytometer and analyzed by FlowJo (RRID:SCR_008520). SNU-16 and KATOIII were seeded in 6-well plates at a density of 5 × 10 5 cells per well with 10% FBS 1640 medium, and were ...