Accumulation of fat molecules is detrimental to the cell. Researchers have made a breakthrough in understanding how our cells manage to stay healthy by recycling important fat molecules. Their study ...

Macroautophagy is a process in which cellular contents are degraded by lysosomes or vacuoles and recycled. Double-membraned structures called autophagosomes enclose cellular material and then fuse ...

The process involves formation of a vesicle called autophagosome, which encapsulates the cellular waste. The autophagosome then fuses with another type of vesicle called lysosome. The fused stage ...

After phosphorylation, AMPK can govern autophagosome formation through recruiting downstream autophagy-related proteins to the autophagosome formation site. Finally, the AMPK-SIRT1 signaling pathway ...

Great progress has been achieved recently in identification and characterization of the conserved and plant-unique regulators involved in the MVB and autophagosome pathways. In this review, we present ...

Immunofluorescence studies revealed that miR-29b replacements enhanced the bortezomib-induced accumulation of ubiquitinated proteins but did not reveal aggresome or autophagosome formation.