For the first time, researchers have directly visualized how newly formed cellular organelles leave the endoplasmic reticulum (ER) and transition onto microtubule tracks inside living cells. This new ...

Institute of Biochemistry and Molecular Medicine (IBIMOL-CONICET), School of Pharmacy and Biochemistry, University of Buenos Aires, Buenos Aires, Argentina The local enrichment of PI3P in ...

Revised: This Reviewed Preprint has been revised by the authors in response to the previous round of peer review; the eLife assessment and the public reviews have been updated where necessary by the ...

Altmetric provides a collated score for online attention across various platforms and media. See more details Plants distribute many nutrients to chloroplasts during leaf development and maturation.

Upon autophagy induction, ZDHHC13 is recruited to autophagosome formation sites together with ATG9A. ULK1 is palmitoylated at Cys 927 and Cys 1003 residues by ZDHHC13, and the ULK1 complex are ...

Pre-autophagosome membrane captures damaged mitochondria and other cytosolic components to become an autophagosome. Autophagosome fuses with lysosome and the materials inside are degraded. Researchers ...

Article Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Autophagy, a conserved eukaryotic ...

Department of Pharmaceutical Chemistry and Small Molecule Discovery Center, University of California, San Francisco, California 94158, United States ...

Macroautophagy is a degradation process fundamental for (eukaryotic) cellular homeostasis, in which cytosolic material is engulfed by a double-membrane autophagosome for delivery to a lytic ...