Methods: We characterized tumor-infiltrating T cells by immunohistochemistry, flow cytometry and T cell receptor sequencing ... No animals were excluded from the efficacy analysis. Paraffin sections ...

Tissue vaccines are harvested directly from tumors and are used to immunize the animal or the patient. They are antigenically rich, in that they are comprised of not only neoplastic cells but also ...

Results Immunofluorescence and cytometry suggested entheseal resident CD4+ and CD8+ T cells with a resident memory phenotype (CD69+/CD45RA-) and tissue residency gene transcripts (higher NR4A1/AhR and ...

To support physicians in treating cancer patients, oncology laboratories can benefit from adopting end-to-end automation of flow cytometry workflows. Rapid advances in automation are improving ...

Tumor-associated macrophages (TAMs) are a phenotypically diverse, highly plastic population of cells in the tumor microenvironment (TME) that have long been known to promote cancer progression. In ...

Developing a deep learning algorithm for automated p53 immunohistochemistry digital image analysis in prostate cancer. This is an ASCO Meeting Abstract from the 2025 ASCO Genitourinary Cancers ...

Breakthrough in childhood brain cancer research could heal treatment-resistant tumors, keep them in remission Potential new therapy for childhood brain cancer is effective in infiltrating, killing ...

Background Treatment strategies for Crohn’s disease (CD) suppress diverse inflammatory pathways but many patients remain ...

Jan. 28, 2025 — A new study shows that asymptomatic brain metastasis is more common in stage 4 breast cancer patients than previously believed. The study suggests ... Route of Entry for Semliki ...

For solid tumors, however, the efficacy of CAR T-cell treatments has been limited and progress “more incremental,” Christian Hinrichs, MD, with Rutgers Cancer Institute in New Brunswick ...