It is a unique member of the plastic family as it can be broken down into its constituent units (or monomers) by PETases, which are enzymes that degrade PET. Until now, scientists have discovered ...

Institute for Drug Discovery, Leipzig University Medical School, Brüderstraße 34, Leipzig 04103, Germany Faculty of Bioengineering and Bioinformatics, Lomonosov Moscow State University, Leninskie Gory ...

Bacterial insertion sequences (IS) are small DNA segments (<2.5 kb) with a simple genetic organization. Most IS elements exhibit short terminal inverted repeat sequences (IR) and encode a transposase, ...

Expert Rev Anti Infect Ther. 2013;11(12):1333-1353. Form in which it is administered CMS (inactive pro-drug), slow and incomplete conversion to colistin (active moiety) Polymyxin B sulfate (active ...

Enzyme mechanisms are the chemical transformations, and the steps within them, generated by enzymatic action on substrates. The mechanism of enzyme catalysis is similar in principle to other types ...

The majority of the isolates produced extended-spectrum beta-lactamase (ESBL), mainly CTX-M-15, and showed multidrug resistance (MDR) profiles. Seven carbapenemase-producing isolates with GES-5 or OXA ...

Department of Pharmacology and Toxicology, College of Veterinary Medicine, Henan Agricultural University, China; ...

pH is a measure of how acidic or alkaline a solution is. The diagram below shows what happens to an enzyme when denaturation occurs. Each enzyme has an optimum pH but it also has a working range ...

The Maine CDC is excited to announce that we are modernizing our Tuberculosis (TB) reporting system. Currently, inactive TB (also known as Latent TB Infection or LTBI) cases and suspect and confirmed ...

During the peer-review process the editor and reviewers write an eLife assessment that summarises the significance of the findings reported in the article (on a scale ranging from landmark to useful) ...