During the peer-review process the editor and reviewers write an eLife assessment that summarises the significance of the findings reported in the article (on a scale ranging from landmark to useful) ...

It is a unique member of the plastic family as it can be broken down into its constituent units (or monomers) by PETases, which are enzymes that degrade PET. Until now, scientists have discovered ...

Engineered enzymes are poised to have transformative impacts across applications in energy, materials, biotechnology, and medicine. Recently, machine learning has emerged as a useful tool for ...

Rubisco is the enzyme responsible for carbon fixation in plants, algae and many bacteria. A screen of a comprehensive library of rubisco variants (each with a different single-amino-acid mutation ...

Revised: This Reviewed Preprint has been revised by the authors in response to the previous round of peer review; the eLife assessment and the public reviews have been updated where necessary by the ...

Temperature affects enzyme-catalysed reactions by influencing the rate at which they occur. For a reaction to occur between an enzyme and substrate the two molecules need to collide. At lower ...

Researchers found ways to tackle a months-long outbreak of multidrug-resistant bacteria sinks of a paediatric ward at the ...

Thirty years of carbapenemase epidemiology demonstrated that these broad-spectrum enzymes might be split in two groups, the “Big Five” carbapenemases and the “rare” carbapenemases. The “Big Five” ...

We aimed at identifying key points that could help assess the risk of CR infection in HM patients and improve their survival. Figure 1. Worldwide distribution of carbapenemase enzymes depending on ...

Not metalloenzyme carbapenemase, guiana extended spectrum ... of their presence in Enterobacteriaceae. In general, these enzymes are only slightly inhibited by clavulanic acid and EDTA, and ...