Joint injury induces rapid and sustained diversification of resident and infiltrating synovial macrophage phenotypes, underpinning osteoarthritis-associated synovitis.

A European research collaboration has found that besides regulating the fusion of mitochondria, Mitofusin 2 also ensures protein quality control. This discovery could open up new routes to treating Ch ...

For decades, aging has been regarded as a sign of irreversible pathologies, weakness, and dependence. Anti-aging remedies ...

In general, chemotherapy medications work by attacking cells or by preventing them from growing and dividing. Cancer cells tend to grow and divide rapidly and uncontrollably, and many chemotherapy ...

Newly discovered brain cells count each bite before sending the order to cease eating a meal. Columbia scientists have found specialized neurons in the brains of mice that order the animals to ...

Caspase recruitment domain 9 (Card9), one of the IBD susceptibility genes, has been shown to protect against intestinal inflammation and fungal infection. However, the cell types and mechanisms ...

Cell proliferation is the process that results in an increase of the number of cells, and is defined by the balance between cell divisions and cell loss through cell death or differentiation. Cell ...

Division of Multi-Organ Transplantation, Department of Surgery, University of California, San Francisco, San Francisco, United States Bakar Computational Health Sciences Institute, University of ...

Bruce Rapport Faculty of Medicine, Technion–Israel Institute of Technology, Haifa, Israel (I.R.H., N.K., C.B., O.C.). The Clinical Research Institute at Rambam ...

Populations of cells can be perturbed by various chemical and genetic treatments and the impact on the cells’ gene expression (transcription, i.e. mRNA levels) and morphology (in an image-based assay) ...