Just like your body has a skeleton, every cell in your body has a skeleton—a cytoskeleton to be precise. This provides cells with mechanical resilience, as well as assisting with cell division.

More information: Françoise Boismal et al, Proteomic and secretomic comparison of young and aged dermal fibroblasts highlights cytoskeleton as a key component during aging, Aging (2024). DOI: 10. ...

However, most animal cells have complex morphologies because the membrane adheres strongly to the cytoskeleton. In animal cells, movement of membrane into an endocytic vesicle or lamellipodium ...

Similarly to mice that lack other regulators of the cytoskeleton, HEM1-deficient T cells showed decreased activation and proliferation compared with wild-type T cells. Surprisingly, some T-cell ...

Caltech researchers demonstrated a new method to use light to control active matter—a kind of material made up of individual ...

In our lab, we aim to elucidate the interplay of clathrin structures with the actin cytoskeleton and cellular adhesions. This work enables us to apply our findings to understand disease processes and ...

Our ultimate goal is to define if manipulating the cytoskeleton of cancer cells will lead to improved efficacy of therapeutic approaches in patients with metastatic disease, with a special focus on ...