Investigating chromatin's 3D architecture reveals its influence on gene regulation, shedding light on mechanisms underlying ...

Unusual nucleic-acid structure may have role in regulating some genes.

So how does your DNA know when it's in a blood cell versus an olfactory cell, for example? How does it know which genes need to be "switched on"? How does a cell know and carry out its function?

Researchers at Washington University School of Medicine in St. Louis have revealed the structure of a key protein involved in ...

Researchers at MIT and Arizona State University have designed a computer program that allows users to translate any free-form drawing into a two-dimensional, nanoscale structure made of DNA.

For the first time, a team of researchers have identified a new DNA structure inside cells that has an entirely different shape to the iconic “double helix” shape uncovered by Watson and Crick ...

And the i-motif is not the first four-stranded structure to be found in human cells; scientists already did that with the discovery of G-quadruplex DNA in humans in 2013.

A critical role for two proteins in chromatin structure has been uncovered by researchers. Their breakthrough helps explain how DNA is organized in our cells. This discovery could lead to a better ...

Find out how the structure of DNA was discovered by Francis Crick and James Watson, and why the discovery revolutionized science and medicine ...

When you think of DNA, odds are, you picture the famous double helix, a ladder-like structure elegantly twisted like a corkscrew. But DNA doesn't always assume this form.

A new DNA structure inside human cells known as the “i-motif”, has been identified by scientists. This form resembles a twisted “knot” of DNA, instead of the well-known double helix first ...

The first step in DNA replication requires the assembly of a group of proteins called the Origin Recognition Complex (ORC). Researchers have determined how the ORC assembles during the cell ...