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鲨鱼源纳米抗体 79C11 靶向沙贝病毒 S2 保守表位,开启广谱抗病毒新征程
为解决 Omicron 亚变体导致 RBD 靶向抗体失效的问题,广州医科大学等单位的研究人员开展鲨鱼源纳米抗体研究。他们发现 79C11 能中和多种病毒,且靶向 S2 保守区域。这为研发抗新冠及其他 sarbecovirus 药物和疫苗提供新思路,值得一读。
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