In total, 11 abstracts on givinostat were accepted for presentation at the Congress, including two for an oral presentation ...

Mutations in the DMD gene prevent the production of functional dystrophin, causing the dystrophin-associated protein complex (DAPC) to break down. This makes muscle fibres more vulnerable to damage ...

The study reveals that dystrophin's C-terminal domain interacts differently with the two major dystrobrevin isoforms, which bind to dystrophin. Variations in the amino acid composition of dystrobrevin ...

Duchenne Muscular Dystrophy protein interactions revealed, paving way for targeted therapies. Study has unveiled the intricate relationship between dystrophin, a protein essential for muscle ...

A groundbreaking study has shed light on the complex interactions between dystrophin, a protein critical to muscle stability, and its partner protein, dystrobrevin, offering new pathways for ...

A groundbreaking study has shed light on the complex interactions between dystrophin, a protein critical to muscle stability, and its partner protein, dystrobrevin, offering new pathways for ...

The Dystrophin-associated protein complex promotes cytokinesis efficiency The importance of regulating cell–substrate interactions during cytokinesis has been well-studied in cell culture (Taneja et ...

Synopsis Building on a Drosophila RNAi modifier screen, this study identifies regulators of cell-cell and cell-matrix interactions that enhance cytokinesis efficiency in epithelial tissues, revealing ...

Abstract Background —Genetic mutations of dystrophin and associated glycoproteins underlie cell degeneration in several inherited cardiomyopathies, although the precise physiological role of these ...

Using this methodology, we evaluated a series of Dystrophin-associated protein complex (DAPC) candidates and identified that the combination of Utrophin and α- Sarcoglycan yielded highest ...