In a cohort of TRANSCEND FL, the chimeric antigen receptor T-cell therapy liso-cel showed a 95% overall response rate in ...

In a remarkable scientific breakthrough, researchers have transformed a historically deadly fungus into a potential weapon in the fight against leukemia, a cancer that kills 23,670 ...

References Hallek M. Chronic lymphocytic leukemia: 2025 update on the epidemiology, pathogenesis, diagnosis, and therapy. Am J Hematol. 2025;100 (3):450-480. doi:10.1002/ajh.27546 American Cancer ...

The spleen may become swollen and enlarged after an injury or infection. An enlarged spleen, or splenomegaly, may also indicate congestion or a blockage resulting from a growth or blood clot.

Later-stage CLL means your symptoms or test results show certain changes, including: Increased number of lymphocytes (a type of white blood cell) Enlarged lymph nodes Enlarged spleen and/or liver ...

Lymph node biopsy is typically unnecessary for diagnosing CLL, but may be essential in challenging cases or to confirm the transformation of CLL into an aggressive lymphoma (Richter transformation). 1 ...

A doctor has issued a warning over a common cancer that affects people of all ages, but may be hard to spot thanks to its ...

Acute Leukemia with Rupture of the Spleen as the Initial Symptom Authors: Irving N. Wolfson, M.D., Edmund J. Croce, M.D., and Franklin K. Fite, M.D. Author Info & Affiliations Published October 28 ...

Both infections and injuries cause an enlarged spleen, and there may be no warning symptoms. As the spleen increases in size, the risk of a spleen rupture also increases. Sharp pain in the left side ...

The splenectomy led to the discovery of cancerous cells that had entered Pollock’s spleen and produced a large tumor. Doctors told him he had chronic lymphocytic leukemia (CLL), a diagnosis that put ...

You might also have an enlarged liver or spleen, or enlarged lymph nodes stage 4 - you have a high number of lymphocytes and a low number of platelets. You might also have an enlarged liver or spleen, ...