The epithelioid granuloma is particularly interesting in this regard as it is also observed in several bacterial infections of the gut. Aims and methods: We hypothesised that genetic or environmental ...

Tumor necrosis factor (TNF) alpha production within the granuloma guides the fusion of epithelioid histiocytes, forming the classic multinucleated giant cells. 5 Of interest, sarcoidal granulomas also ...

Epithelioid granulomas seen in Crohn’s disease show a specific geographic arrangement with multinuclear giant cells and T lymphocytes, similar to granulomas observed in many infectious diseases.

Abstract e17594 Background: Perivascular epithelioid cell tumors (PEComas) are rare soft tissue tumors composed primarily of epithelioid cells and found most commonly in perivascular spaces.

A pyogenic granuloma is when you have a red bump on your skin that bleeds easily. Learn about the causes, symptoms, treatment, and more.

Kendric Cromer, 12, the first commercial patient for Bluebird Bio’s gene therapy to cure his sickle cell disease, in the hospital as his bone marrow stem cells were being removed for gene editing.

Sarcoidosis is a multisystem disease characterized by noncaseating epithelioid cell granuloma. Although the etiology and pathogenesis of sarcoidosis is unknown, it is believed to be related to genetic ...

In most cases, granuloma macrophages were immunoreactive for CD11c and CD206. However, in 5 cases of lymphogranuloma, numerous CD206-negative cells were observed. CD163 and CD10 were diffusely ...

Detecting non-cavitary epithelioid cell granuloma by gastrointestinal biopsy is important in the initial diagnosis of Crohn’s disease (CD). In the present study, we aimed to determine the rate of ...

Background: Cardiac involvement is an important determinant of mortality among sarcoidosis patients. Although granulomatous inflammation is a hallmark finding in cardiac sarcoidosis, the precise ...

Similarly, cell-cell interactions during infection and granuloma formation may also contribute to type 2 polarization and epithelioid transformation. Coculture of macrophages with platelets has found ...