The addition of nab-paclitaxel to gemcitabine and cisplatin did not improve survival in advanced biliary tract cancer.

The glucoregulatory functions of pancreatic islets are affected by their surrounding niche and spatial organization. Here, bioengineered stem-cell derived islet niches use bioprinting-based ...

Delcath Systems, Inc. ("Delcath" or the "Company"), an interventional oncology company focused on the treatment of primary and metastatic cancers of the liver, today announced an update to the ...

The lab of Dr. Mark Magnuson, Louise B. McGavock Professor and professor of molecular physiology and biophysics at Vanderbilt ...

Ultrasound usually shows dilated intrahepatic bile ducts with normal or dilated extrahepatic bile ducts depending on the location of the obstruction. Conventional CT may help detect the primary ...

Step 4: p-cMGP is secreted into the extracellular matrix or the circulation to inhibit soft tissue calcification, VSMC (vascular smooth muscle cell) trans-differentiation into OPC (osteochondrogenic ...

Correspondence to Dr Guangchuan Wang, Gastroenterology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong, China; riverwang{at}126.com; Dr Shan Shan, Liver ...

Design Flow cytometry, immunohistochemistry, confocal imaging and gene expression analyses determined the phenotype, functional/transcriptomic profile and tissue topography of MerTK+ ...

"At Mammoth, we have always believed in the therapeutic potential of CRISPR, and this study demonstrates that ultracompact systems can be potent and delivered in a single AAV vector to tissues outside ...

New research shows potent in vivo gene editing in skeletal muscle of non-human primates by a novel, ultracompact CRISPR system delivered via a single AAV vector This study describes the discovery ...

that establishes proof-of-concept of NanoCas™, the first ultracompact CRISPR system capable of efficient extrahepatic editing when delivered systemically using a single adeno-associated viral (AAV) ...