LONDON, GREATER LONDON, UNITED KINGDOM, July 4, 2025 /EINPresswire.com/ -- The chronic traumatic encephalopathy market size has shown commendable growth in recent years, expanding from $1.39 billion ...

Lung macrophages play a pivotal role in diseases like idiopathic pulmonary fibrosis. Two types of macrophages—the white blood ...

Taken together, studies on fibrogenesis in the liver (and other organs as well) are now pushed forward a lot, hopefully resulting in new impulses for therapy and diagnosis.

Thus, fibrogenesis in NASH seems to result from the combined actions of several autocrine/paracrine signalling loops that re-enforce Hh pathway activation and OPN production in different types of ...

Our results revealed that Jnk1 is crucial for liver fibrogenesis, but other cells than hepatocytes mediate this effect. Hence, we investigated whether bone marrow–derived cells (BMDC) are essential in ...

Special Article Archive Some Biochemical Aspects of Fibrogenesis and Wound Healing Author: David S. Jackson, Ph.D. Author Info & Affiliations Published October 23, 1958 N Engl J Med 1958;259: 814 ...

This study identifies TGF-β1/p65/MAT2A pathway that is involved in the regulation of intracellular SAM concentration and liver fibrogenesis, suggesting that this pathway is a potential therapeutic ...

Liver cirrhosis is increasingly becoming the major cause of global health burden. It originates through a dynamic process of liver fibrogenesis and fibrosis. Excessive accumulation of extracellular ...

Fibroblast growth factor 21 blocks hepatic lipid influx and accumulation, prevents Kupffer cell activation, and inhibits the formation of hepatic lipid- and scar-associated macrophages, thereby likely ...

Liver fibrogenesis is accompanied by upregulation of lysyl oxidase enzymes, which catalyze oxidation of lysine ε-amino groups on the extracellular matrix proteins to form the aldehyde containing amino ...

Although for liver fibrogenesis not yet proven, subgroups of monocytes can differentiate into fibroblast-like cells (fibrocytes) after entering the damaged tissue.