If you want to build a foundational understanding of genomics in both health and disease, it's important to be able to distinguish between the different type of genetic mutations that can occur. Here, ...

Frameshift mutations in the RIZ gene were found in 17% of melanoma samples and 8.6% of naevi, but we could not demonstrate any missense mutations in the exons of RIZ1.

Frameshift mutation of the Dok1 gene in CLL. (a) cDNA samples from 11 normal and 46 CLL samples were amplified using the primer set F4/R4 and screened for detection of Dok1 mutation by ...

Frameshift deletion mutation in ORF7a may provide fitness advantage to Australia's SARS-CoV-2 delta variants. News-Medical, viewed 05 December 2024, https: ...

In a paper published on aBIOTECH, the authors obtained viable knockout mutants with developmental defects by introducing frameshift mutations to C -terminus sequence of three essential protein kinase ...

A recent study by Canadian and US researchers demonstrates how frameshift signals of coronaviruses represent a viable target for developing novel therapeutics with broad-spectrum activity – not ...

It demonstrated impressive neoantigen-specific T cell responses in all evaluable participants, inducing durable and robust immune responses against frameshift peptide neoantigens. Lynch Syndrome is ...

Vaccination of MSI-H colorectal cancer patients with frameshift peptide antigens: A phase I/IIa clinical trial. Matthias Kloor , Miriam Reuschenbach , Julia Karbach , Mohammad-Reza Rafiyan , ...

Attitudes toward prevention options in Lynch syndrome (LS): Comparing frameshift peptide vaccination (FSPVAX), colonoscopy (COLO), and aspirin (ASA) chemoprevention. Michael J. Hall , Emma D Riggs , ...