The deletion of GSTT1 and GSTM1 genes result in loss of enzyme activity. A few studies evaluated the response to treatment and the polymorphisms of GSTT1 and GSTM1. The aim of this work is to make the ...

The distribution of polymorphisms related to glutathione S-transferases (GST) has been described in different populations, mainly for white individuals. We evaluated the distribution of GST mu (GSTM1) ...

Discussion: Our study revealed that GSTM1 and GSTT1 can protect renal tubular cells against cisplatin-induced nephrotoxicity and ferroptosis, and genetic screening for GSTM1 and GSTT1 polymorphisms ...

Independent and combined effects of GSTM1, GSTT1 and GSTP1 IIe105Val polymorphisms with the risk of T2DM have been described in a number of original investigations, and the association of GSTs gene ...

A recent meta analysis of several literature sources reveals evidence linking polymorphisms of both the GSTM1 and GSTT1 enzymes, which are involved in kidney detoxification of carcinogens to the risk ...

Our results suggested that the polymorphisms of GSTT1 and GSTM1 were associated with the methylation of arsenic, especially the levels of DMA and SMI.

For the analysis of GSTM1 or GSTT1, after discarding 4 articles [24-27] because they were not related to endometrial cancer and 1 article [5] due to insufficient genotype data, 6 case control studies ...

In conclusion, our study results suggest that GSTT1 null genotype is associated with the RCC susceptibility in Caucasians and Asians, and the dual null genotype of GSTM1-GSTT1 is associated with RCC ...

GSTM1 and GSTT1 catalyze detoxification of reactive oxygen and products of lipid peroxidation 14. Epidemiologic studies show that null genotypes for GSTM1 and GSTT1 are related to the increase of ...

Polymorphisms of GSTP1, GSTT1, GSTM1, MTHFR, TS, ERCC1, and ERCC2 in metastatic colorectal cancer treated by first-line mFOLFOX6 chemotherapy. If you have the appropriate software installed, you can ...