Our objective was to extend current knowledge of the genetics of beryllium disease by examining all HLA-DPB1 and HLA-DPR1 gene polymorphisms and the interactions between them. Methods DNA-based typing ...

There were 244 distinct HLA alleles (142 of Class I and 93 of Class II) comprising the classical genes of Class I (A, B, C) and Class II (DPB1, DQB1, DRB1). The alleles and their frequencies ...

SpecHLA reconstructs entire diploid sequences of HLA genes and infers LOH events. It supports HLA-A, -B, -C, -DPA1, -DPB1, -DQA1, -DQB1, and -DRB1 genes. Also, it ...

xinhuamed.com.cn Background The classical human leucocyte antigen (HLA) genes were the most important genetic determinant for Graves’ disease (GD). The aim of the study was to fine map causal variants ...

You will be redirected to our submission process. HLA traveled a long distance from initially being regarded as a transplant antigen to becoming a molecule of interest in the 21st century for the ...

1 Institute of Liver Studies, King's College Hospital, King's College London, London, UK Correspondence to Dr Charalambos G Antoniades, Division of Digestive Diseases, St Mary's Campus, Imperial ...

Objective Tumour heterogeneity represents a major obstacle to accurate diagnosis and treatment in gastric adenocarcinoma (GA). Here, we report a systematic transcriptional atlas to delineate molecular ...

Most autoimmune diseases are associated with certain HLA types. Therefore, spondyloarthropathies (SpA) strongly associated with HLA-B27, are also often classified as autoimmune diseases. This study ...

Retrospective study evaluating the genomic landscape of anal squamous cell carcinoma using liquid biopsy. Tumor tissue modified viral (TTMV)-HPV DNA as a biomarker of treatment efficacy for definitive ...

Objective To investigate the relationship between metabolomic profiles, genome-wide polygenic risk scores (PRSs) and risk of rheumatoid arthritis (RA). Methods 143 nuclear magnetic resonance-based ...