To gain insight into the metabolism changes that occur in somatic cell reprogramming, we examined the metabolome of iPSCs relative to their parental cells of origin.

Figure 1: Continuous single-cell imaging allows tracking of reprogramming cells. The distinction between primary and satellite colonies allowed us to reappraise calculated reprogramming ...

Heart tissue normally can't regenerate after an injury. But now, scientists at Max Planck have shown in mice that reprogramming the energy metabolism of the heart allows it to regenerate after a ...

Engulfment of the tumor-derived particles by macrophages. This causes a metabolic switch by increasing mitochondria reprogramming and oxidative respiration. This switch is archived by mTOR1. Image ...

A Ludwig Cancer Research study has identified a metabolic switch in the immune system's T cells that is essential to the generation of memory T cells—which confer lasting immunity to previously ...

A modified version of iPS methodology, called interrupted reprogramming, allows for a highly controlled, safer, and more cost-effective strategy for generating progenitor-like cells from adult ...

A modified version of iPS methodology, called interrupted reprogramming, allows for a highly controlled, safer, and more cost-effective strategy for generating progenitor-like cells from adult ...

By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center for Cancer Biology and their collaborators demonstrated a remarkable ability to boost the immune system's fight ...

Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of T cells, scientists at the VIB-KU Leuven Center for Cancer Biology and ...

Children born to obese mothers are at higher risk of developing metabolic disorders, even if they follow a healthy diet themselves.

Researchers have identified a hurdle towards an efficient conversion: the cell metabolism. By expressing neuron-enriched mitochondrial proteins at an early stage of the direct reprogramming ...

Unlock New Insights into Cancer Cell Metabolism By understanding metabolic reprogramming in cancer, researchers can develop critical therapies.