Heart tissue normally can't regenerate after an injury. But now, scientists at Max Planck have shown in mice that reprogramming the energy metabolism of the heart allows it to regenerate after a ...

A Ludwig Cancer Research study has identified a metabolic switch in the immune system's T cells that is essential to the generation of memory T cells—which confer lasting immunity to previously ...

Engulfment of the tumor-derived particles by macrophages. This causes a metabolic switch by increasing mitochondria reprogramming and oxidative respiration. This switch is archived by mTOR1. Image ...

Aging is a complex process that has long puzzled scientists. A recent study published in Engineering proposes a new theory called pro-aging metabolic reprogramming (PAMRP), which could change our ...

Activation of macrophages and dendritic cells (DCs) by pro-inflammatory stimuli causes them to undergo a metabolic switch towards glycolysis and away from oxidative phosphorylation (OXPHOS ...

Currently, iPS cells are created by introducing four defined genes to an adult cell. The genes reprogram the adult cell into a stem cell, which can differentiate into many different types of the ...

A modified version of iPS methodology, called interrupted reprogramming, allows for a highly controlled, safer, and more cost-effective strategy for generating progenitor-like cells from adult ...

A modified version of iPS methodology, called interrupted reprogramming, allows for a highly controlled, safer, and more cost-effective strategy for generating progenitor-like cells from adult ...

Children born to obese mothers are at higher risk of developing metabolic disorders, even if they follow a healthy diet themselves.

Unlock New Insights into Cancer Cell Metabolism By understanding metabolic reprogramming in cancer, researchers can develop critical therapies.

Researchers have identified a hurdle towards an efficient conversion: the cell metabolism. By expressing neuron-enriched mitochondrial proteins at an early stage of the direct reprogramming ...