Adding bile acids as farnesoid X receptor agonists to the culture medium supported the growth and development of unique stem ...

Adding bile acids as farnesoid X receptor agonists to the culture medium supported the growth and development of unique stem ...

Adding bile acids as farnesoid X receptor agonists to the culture medium supported the growth and development of unique stem cell-derived hepatic organoids, report researchers from Japan. These ...

Cirrhosis represents an advanced stage of liver disease characterised by distorted liver parenchyma, nodule formation, hepatic dysfunction or insufficiency and reduced intrahepatic blood flow leading ...

The regulatory mechanisms that underlie these phases are common to the development of many organ systems and might be recapitulated or disrupted during stem-cell differentiation and adult tissue ...

Hepatic dendritic cells (DC) unquestionably play important roles in the induction and regulation of immune responses. Due to their paucity, functional characterisation of these important antigen ...

Spheroids are a powerful tool for basic research and to reduce or replace in vivo (animal) studies but are not routinely banked nor shared. Here, we report the successful cryopreservation of ...