Direct detection of secondary structures by single‐molecule sensing using solid‐state nanopores established the lack of pre‐formed structures prior to replication, whereas conditions that enhanced ...

Protein secondary structures, such as α-helices and β-sheets, are the most distinguishable characteristics in a medium-resolution cryo-EM density map, (3) even though amino acids are not discernible ...

In this study, we have proposed a novel mutual information-based feature representation algorithm for pre-miRNA sequences and secondary structures, which is capable of catching the interactions ...

Yet another reason for the difficulty in assessing miRNA biogenesis, despite abundant available data, regards the challenges in prediction of their secondary structures.

For example, it is recognized that bioinformatically derived miRNA secondary structures often differ from experimentally derived structures (45), principally due to overprediction of base-pairing (35) ...

Discover the impact of Shine-Dalgarno sequence on translation initiation in bacterial cells. Explore mRNA stability and secondary structure formation in Rhodobacter sphaeroides genes. Uncover the role ...

This paper culminates years of research on the RNA secondary structure and its role in the regulation of gene expression. We have published an extensive computation-based catalog of potentially ...

Predicted miRNA secondary structure should have higher Minimal Free Energy Index (MFEI) folding and negative Minimal Folding Free Energy (MFE) to differentiate it from other small RNAs. Sequences ...

In this paper the authors have made a systematic study to get a proper secondary structure of the pre-mature miRNA and get the mature miRNA sequence corresponding to it. The similarities of the ...