Feb. 20, 2025 — Biologists have discovered a new type of RNA-splicing regulation that helps to determine which protein-coding exons will be included in messenger RNA ...

AI molecular design tool for de novo design, scaffold hopping, R-group replacement, linker design and molecule optimization.

There are 20 amino acids that create the proteins required for life on our planet — and scientists have now found exactly 14 of them on an asteroid millions of miles away. The asteroid in question, ...

Targeting alterations in both the PI3K-AKT-mTOR and DNA repairs pathways has shown synergy in preclinical studies. Here, the authors a phase I/II clinical trial investigating the combination of ...

Deep generative models are rapidly becoming popular for the discovery of new molecules and materials. Such models learn on a large collection of molecular structures and produce novel compounds. In ...

An artificial intelligence model has created a new protein that researchers say would have taken 500 million years to evolve in nature — if nature were capable of producing such a thing.

Molecular evolution is the area of evolutionary biology that studies evolutionary change at the level of the DNA sequence. It includes the study of rates of sequence change, relative importance of ...

Laboratory of Green S.O.C. − Dipartimento di Chimica, Biologia e Biotecnologie, Università Degli Studi di Perugia, Via Elce di Sotto 8, Perugia 06123, Italy Department of Chemistry, and FRQNT Centre ...

Stratingh Institute for Chemistry, University of Groningen, 9747AG Groningen, The Netherlands ...

The drug restored the cholinergic system and improved memory,” added Moreno. Rafael Rodríguez believes that “this molecule could become a drug to treat the symptoms of dementia, at least during the ...

Water pollution is one of the growing challenges of modern life. Many everyday items, from medications to cosmetics, leave behind residues that don't fully break down after use. These pollutants ...

Molecular Cancer Therapeutics publishes articles on the discovery and preclinical development of novel therapeutic agents for oncology, preclinical studies of approved therapeutics, mechanisms of drug ...