Microscopic characterization of programmed Au NP structures. The Au NPs were functionalized with one or two nucleic acids (for the DNA sequences, synthesis and purification of the three-ring ...

A DNA-based channel that undergoes a nanomechanical change in response to the binding of a specific ligand can be used to selectively transport small-molecule cargo across a lipid bilayer.

Wang R, Wang S, Dhar A, Peralta C, Pavletich NP. (2020). DNA clamp function of the monoubiquitinated Fanconi anaemia ID complex. Nature. 2020;580:278-282. Yang H, Zhou C, Dhar A, Pavletich NP. (2020).