For decades, the dream of fixing harmful mutations in mitochondrial DNA felt out of reach. Scientists have long known these ...

Explore the innovative applications of mRNA technologies beyond COVID-19 vaccines. Learn about the potential and future developments in this groundbreaking field.

NUCLEUS information resources The IAEA's NUCLEUS information resource portal provides access to over 100 scientific, technical and regulatory resources, including databases, applications, publications ...

Discover the bioanalytical strategies crucial for unlocking the potential of LNP-mRNA vaccines. Explore the impact of these strategies on the development and efficacy of mRNA vaccines.

Nucleus articles from across Nature Portfolio The nucleus is the double membrane limited structure within an eukaryotic cell that contains the chromosomes, and where the DNA is replicated or ...

Researchers from the University of Sydney have developed a system that mimics natural selection inside living mammalian cells ...

NUCLEUS信息资源 原子能机构的NUCLEUS信息资源门户提供对包括数据库、应用程序、出版物和培训材料在内的100多个科学、技术和监管资源的访问。 由于NUCLEUS主要面向原子能机构在政府、工业界和科学界的对口方，因此，其中有些资源需要注册。

Antibody–siRNA conjugates (ARCs) are a type of promising drug modalities for cancer therapy. However, initial reports of ARCs present the gene knockdown effect only in limited tissues (e.g., muscles) ...

脑声小店基于深度科研洞察，专注为动物实验提供"简器械·精实验"解决方案。我们突破高精设备局限，开发手工定制化仪器及配件，通过科研巧思将基础工具转化为创新实验方案。产品涵盖行为学装置、操作辅助工具等，使实验室在保持操作简效的同时，实现精细化数据采集，助 ...

Messenger RNA (mRNA) vaccines hold promise for creating new and improved immunizations; however, their delivery is challenging in terms of compliance, reactogenicity, cost and scalability.