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Agonists of immune checkpoint modulators for treating autoimmune and inflammatory disorders have shown high potential in immunotherapy. P-selectin glycoprotein ligand 1 (PSGL-1) is known to exert ...
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编辑推荐: 推荐 炎症、血栓和免疫失调是多种疾病的病理基础,现有动物模型存在局限。研究人员构建人 PSGL-1 转基因(hPSGL-1 TG)巴马小型猪模型,发现其出现炎症、心功能不全等,揭示 hPSGL-1 在相关病理中的关键作用,为研究和靶向治疗提供平台。
推荐 炎症、血栓和免疫失调是多种疾病的病理基础,现有动物模型存在局限。研究人员构建人 PSGL-1 转基因(hPSGL-1 TG)巴马小型猪模型,发现其出现炎症、心功能不全等,揭示 hPSGL-1 在相关病理中的关键作用,为研究和靶向治疗提供平台。
The kinetic and mechanical properties of L-selectin interacting with monomeric and dimeric P-selectin glycoprotein ligand-1 (PSGL-1) were characterized using an atomic force microscope (AFM). A ...
P选择素糖蛋白配体1 (PSGL-1)酶联免疫分析试剂盒 保证质量,灵敏性高、特异性强、重复性好等优点已经得到广大客户的认可,您可放心,且我司有专门的售后部门对您进行全线跟踪。
PSGL F1 23 PC 1 Schedule The schedule hasn’t been released yet so we are still unaware of where round 2 will be held and how many races are going to be run this season.
P-selectin glycoprotein ligand-1 (PSGL-1) is expressed in macrophages and plays a vital role in synergizing for a more robust anti-tumor response. However, there are few studies about PSGL-1 ...
These studies underscore the function of PSGL-1 as a key negative regulator of effector and memory T cell differentiation and suggest that PSGL-1 may limit excessive stimulation of memory T cells ...
Events mediated by the P-selectin/PSGL-1 pathway play a critical role in the initiation and propagation of venous thrombosis by facilitating the accumulation of leukocytes and platelets within the ...
尽管此前有报道发现PSGL-1的表达可抑制HIV-1复制,但PSGL-1抑制HIV-1病毒活性的机制尚未阐明。 在该研究中,作者发现整合入HIV病毒颗粒的PSGL-1分子可通过阻断病毒与靶细胞结合,从而抑制病毒感染。
PSGL-1 and CD43 are surface glycoproteins expressed on blood CD4 T cells to bind to selectins for T cell tethering, rolling, and migration into inflamed tissues. The PSGL-1 level is greatly ...