eLife is a non-profit organisation inspired by research funders and led by scientists. Our mission is to help scientists accelerate discovery by operating a platform for research communication that ...

The phase 1 trial is testing the safety tolerability, pharmacokinetics, and pharmacodynamics of PVT201 in healthy volunteers and patients.

Gluten may cause inflammation in people who are sensitive to it. This can lead to gastrointestinal symptoms like stomach pain, bloating, and vomiting. In people with celiac disease, it can also lead ...

Inflammation is the body's response to a harmful substance, such as a virus, when the immune system tries to fix the problem and heal damaged cells. Acute (short-term) inflammation can help ...

Nonspecific portal inflammation, which progresses to periportal fibrosis, is the most common histological finding in PSC. A more specific finding is an 'onion-skin' pattern of periductal fibrosis ...

Inflammation is a normal part of the body's immune response to pain, injury, or infections. Acute (short-term) inflammation helps heal the body and protect against infections. However ...

Inflammation is a biological response to harmful stimuli, such as pathogens, damaged cells or irradiation. It is a protective attempt by the organism to remove injurious stimuli and to initiate ...

The second liver biopsy revealed lymphoplasmacellular portal and periportal inflammation with interface hepatitis compatible with AIH and mild cholestasis (hematoxylin and eosin ×200).

Inflammation is a natural body response to injury or infection, but chronic inflammation is linked to various health issues. Acute inflammation is temporary, while chronic inflammation lasts ...