Plasmacytoid dendritic cells are known for their ability to produce large amounts of type I interferons, which can contribute to autoimmunity. Research now shows that this pathogenicity involves a ...

Modern Pathology (2023). [4] Lineage-specific RUNX2 super-enhancer activates MYC and promotes the development of blastic plasmacytoid dendritic cell neoplasm. Nature Communications (2019).

Introduction Since the early reference to plasmacytoid dendritic cells (pDCs) in the paracortical area of reactive lymph nodes in 1958 by Lennert and Remmele, [1] an abundance of new information ...

Learning Objectives: 1. Identify the key roles of dendritic cells in cancer immunotherapy, including their use as antigen-loaded vaccines and intratumoral adjuvants. 2. Explain the strategies used to ...