Scientists Discover “Genetic Weak Point” of Critically Endangered Apennine Brown Bears
Only about 50 Apennine brown bears remain in the wild, and new research sheds light on a key challenge to their survival. The ...
Mutation increases enzyme in mouse brains linked to schizophrenia behaviors
A genetic mutation found in two human patients with schizophrenia also increased schizophrenia-related behaviors in mice with ...
jmg.bmj18 天
De novo mtDNA point mutations are common and have a low recurrence risk
mumc.nl Background Severe, disease-causing germline mitochondrial (mt)DNA mutations are maternally inherited or arise de novo. Strategies to prevent transmission are generally available, but depend on ...
来自MSN3 天
Mutation in mouse brain linked to schizophrenia: U of I scientists
Researchers at the University of Illinois have found a direct link between a genetic mutation and schizophrenia. The ...
jmg.bmj16 天
Somatic point mutations occurring early in development: a monozygotic twin study
mcgill.ca The identification of somatic driver mutations in cancer has enabled therapeutic advances by identifying drug targets critical to disease causation. However, such genomic discoveries in ...
In vitro reconstitution of meiotic DNA double-strand breaks: A long-standing challenge solved
In a study published in Nature, researchers report the successful in vitro reconstitution of meiotic DNA double-strand breaks ...
Medical Xpress18 天
Mutations in two gene pairs point to a promising drug target in 5% of adult cancers
These cancers have mutations in one of two genes, FOCAD or TCC37. "These cancers are a huge unmet medical need, because we don't have effective drugs for them," said Francisca Vazquez, co-senior ...