A new study published in Nature Neuroscience has found that male and female mice rely on different brain circuits to process threatening situations, even though they behave in much the same way. While ...

2015Cell-Type-Specific Activity in Prefrontal Cortex during Goal-Directed BehaviorNeuron 87:437–450 Google Scholar 54. Yuste R. 2015From the neuron doctrine to neural networksNat. Rev. Neurosci 16:487 ...

In everyday life, our brains adapt to new situations using the prefrontal cortex. A team of neuroscientists discovered a special class of neurons in the prefrontal cortex that enable flexible behavior ...

Scientists achieved “a milestone” by charting the activity and structure of 200,000 cells in a mouse brain and their 523 million connections.

The developmental progress from daredevil teen to risk-averse senior is more complex than we thought, according to a new study that identified changing relationships between neural structures related ...

While the overlap in biological processes associated with rhythmic transcripts differs by region and sex, circadian rhythm signaling is among the top 10 pathways in the mouse mPFC and the human PFC ...

In the course of evolution, the prefrontal cortex develops to maximum relative mass in the human brain. That large increase in mass is attributable to the disproportionate development of connective ...

We examined functional and structural cellular phenotypes linked to synaptic transmission in deep layer pyramidal neurons of the prefrontal cortex in male and female mice carrying a heterozygous, loss ...

The prefrontal cortex also affects your personality. A historical example of what happens when a person’s prefrontal cortex is damaged occurred in the mid-1800s. When railroad worker Phineas Gage’s ...

More information: Le Gao et al, Single-neuron analysis of dendrites and axons reveals the network organization in mouse prefrontal cortex, Nature Neuroscience (2023). DOI: 10.1038/s41593-023-01339-y ...