This dissertation focuses on the glial protein GFAP and Alexander disease, a severe neurological disorder primarily affecting young children. Mutations in the GFAP gene disrupt astrocyte function, ...

Cortical formation in the developing brain is a highly complicated process involving neuronal production (through symmetric or asymmetric cell division) interaction of radial glia with neuronal ...

Upon glial depletion, Paneth cell secretion is disrupted leading to dysmorphic granules ... S100B, SOX10, PLP1, and GFAP expression across the radial axis of the human small intestine. A) – D) ...

Upon glial depletion, Paneth cell secretion is disrupted leading to dysmorphic granules ... S100B, SOX10, PLP1, and GFAP expression across the radial axis of the human small intestine. A) – D) ...

In general, chemotherapy medications work by attacking cells or by preventing them from growing and dividing. Cancer cells tend to grow and divide rapidly and uncontrollably, and many chemotherapy ...

All six studies revealed consistent improvement of sensorimotor outcomes with rGDF11. rGDF11-treated rats showed increased cortical vascularization and radial glia in the ventricular zone. Serum ...

Induced pluripotent stem cells (iPSCs), which greatly circumvent the ethical issue of human embryonic stem cells (ESCs), can be induced to differentiate to dopaminergic (DA) neurons, and hence be used ...

Here, we highlight the complex molecular signaling that takes place in neurons, glial cells and the blood-brain barrier following ischemic insult. We also describe the evidence of TRPM2 ...

Neurons are cells in the body that are responsible for transmitting electrical signals through the nervous system. Different types of neurons affect the ability to move, which begins as an impulse, or ...

It feels like the Splinter Cell remake has been on its way for a while now, which isn't helped by the fact it's been over three years since we heard anything official about the game. From what we ...

To better model how neurons fire and interact with glia, some scientists place the cells into a brain or grow them in an organoid. Others have produced little spheres of human neural tissue by ...

However, how birth-associated metabolic changes affect the fate of tissue stem cells, especially NSCs, is largely unknown. Sawamoto’s group focused on metabolic changes in radial glia (RG), the ...