Building on more than two decades of research, a study by MIT neuroscientists at The Picower Institute for Learning and Memory reports a new way to treat pathology and symptoms of fragile X syndrome, ...

Johns Hopkins University School of Medicine researchers have discovered a dual regulatory mechanism safeguarding ...

MIT neuroscientists have made a breakthrough in treating fragile X syndrome by leveraging a novel neurotransmitter signaling ...

A photothermal, nanoparticle-based deep brain stimulation system restored motor skills in mice with Parkinson’s-like disease ...

在慢性疼痛过程中脊髓背角区（SDH）的星形胶质细胞增生比神经损伤后的小胶质细胞增生更明显。为探究SDH区星形胶质细胞Gpr37l1是否参与疼痛，研究人员首先通过单细胞测序发现Gpr37l1富集表达SDH区星形胶质细胞，免疫荧光实验证实Gpr37l1可 ...

B-2D, a brain receptor targeted by ketamine. Using cryo-EM, they visualize how ketamine binds to the receptor, controlling ...

New research sheds light on how ketamine affects the brain by targeting a specific NMDA receptor subtype, GluN1-2B-2D.

Ketamine has received a Hollywood makeover. It used to be known as a rave drug (street name special K) and cat anesthetic.

Nerve cells called pro-opiomelanocortin (POMC) neurons were found to be responsible for post-feeding sugar consumption.

Researchers at UC Davis have achieved total chemical synthesis of the psychoactive compound ibogaine and its analogs from pyridine. The discovery will make it easier to explore the therapeutic ...

To visualize specific receptors in single neuron types within the crowded MB neuropil, the authors use existing dopamine receptor alleles tagged with 7 copies of split GFP to target the reconstitution ...