A new study from Professor Vadim Backman shows that restoring cellular memory prevents cancer cells’ ability to adapt to evade treatment.

SeamlessTx is addressing this challenge with a unique platform that integrates large-scale directed evolution and machine ...

The field of cancer biology and digestive diseases has increasingly focused on the intricate relationship between microbiota homeostasis and metabolic reprogramming. Metabolic reprogramming is a ...

Cancer cells often use epigenetic changes to resist treatment, a major factor particularly in late-stage deaths from ovarian cancer. One potential epigenetic marker, DNA secondary structures known as ...

The ability to create stem cells from non-embryonic cells, through the process of reprogramming, lifted the ethical hindrance and is driving stem cell research in a new direction at a rapid pace. A ...

Reprogramming involves inducing the expression of four factors, called Yamanaka factors, in cells. The factors must be expressed for 2 to 3 weeks for cells to reach pluripotency.

Dedifferentiation, transdifferentiation and reprogramming could all be exploited to replace lost cells and tissues. Studies are aiming to understand the molecular details of these processes and to ...

One promising strategy to remuscularize the injured heart is the direct cardiac reprogramming of heart fibroblast cells into cardiomyocytes. Researchers have identified TBX20 as the key missing ...

They believe that reprogramming rather than poisoning cells will be less toxic to patients. "What evidence do you have that this treatment is working?" LaPook asked.

Heart tissue normally can't regenerate after an injury. But now, scientists at Max Planck have shown in mice that reprogramming the energy metabolism of the heart allows it to regenerate after a ...