The comprehensive review, which was requested by the CDC, revealed that ISO faces ongoing challenges from its perceived overlap with the National Center for Immunization and Respiratory Diseases, ...

Major new analysis from the Thrombotic Thrombocytopenia Syndrome (TTS) Consortium has provided critical insights into the rare but serious condition known as vaccine-induced immune thrombotic ...

In children, the timing of thrombocytopenia, its extent, and associated clinical features dictate the investigation of pathophysiologic causes and management. Thrombocytopenia is relatively common in ...

Thrombotic thrombocytopenic purpura (TTP) is a rare and life-threatening disorder due to a severe acquired or inherited ADAMTS13 deficiency. So far, therapeutic algorithms almost universally include ...

The 2024 Guidelines for the Primary Prevention of Stroke, recently updated by the American Heart Association and the American Stroke Association, serve as an essential resource for clinicians aiming ...

Flowchart of patients studied in our Department from January to October 2021 with clinical suspicion of TMA. *Patients with clinical symptoms of aTTP whose diagnosis was not confirmed by ADAMTS13 ...

Objectives The association between immune-mediated thrombotic thrombocytopenic purpura (iTTP) and Sjögren disease (SjD) has been poorly investigated. This study presents the first retrospective cohort ...

− cTTP is an Ultra-rare, Potentially Fatal Blood-Clotting Disorder with Limited Treatment Options; Untreated, Acute TTP Events Have a Mortality Rate of >90%1,2 − Approval Based on Totality of Evidence ...

Von Willebrand factor (vWF) plays a crucial role in hemostasis, and elevated levels are associated with risk of thrombosis. Gain-of-function mutations in the C-domain of vWF are linked to an increased ...