编辑推荐： 推荐 为探究调控 Ca2?稳态的基因，研究人员利用 CaMPARI2 传感器结合流式细胞术与 CRISPR 筛选（CaMP-Screen），发现 SOCE 和脂质信号通路关键作用，证实 TIM1 是静息状态下 SOCE 的负调控因子，为 T 细胞功能调控机制提供新视角。

CD300b binding to TIM1 and TIM4 depends on phosphatidylserine. A previous report demonstrated that CD300b recognized TIM1- or TIM4-expressing Ba/F3 cells. 23 To investigate further the binding of ...

TIM-3 may provide a negative costimulatory signal to the T cell, ... Anti-Tim1 does not enhance IFN-γ production in T H 1 cells at any dose of antigen. (PDF 149 kb) Supplementary Fig. 5.