Some cancer survivors who have overcome the odds are facing another diagnosis: heart damage, from chemotherapy, radiation or ...

Experts say ingesting the adulterant could lead to severe cardiotoxicity, ocular damage, and even sudden death.

The authors showed that the cardiotoxicity is probably due to inhibition of one specific target of imatinib, the c-Abl protein kinase. Cardiomyocyte death was largely prevented by deactivation of ...

Cardiotoxicity, however, is an important adverse effect that is observed with the use of this agent. Particularly with concurrent anthracycline treatment, the incidence of cardiotoxicity increases ...

A new meta-analysis published in OMICS: A Journal of Integrative Biology helps shed light on how changes in mitochondria-related gene expression may cause the cardiotoxicity associated with the ...

A second study used genetic variants, in addition to clinical and genetic factors, to identify those at highest risk for anthracycline-related cardiotoxicity. They evaluated 2,977 SNPs in 220 key drug ...