Despite promising science, Precigen has long-faced severe financial challenges and a very short cash runway into 2026. Click ...

Influenza continues to pose a significant global health burden, with seasonal outbreaks causing substantial morbidity and ...

If the clinical sample contains viable virus, cytopathic effects due to the herpes virus replication occur after several days, signaling the recovery of HSV-1/2 and VZV from the sample.

Regulated cell death (RCD) is pivotal in developmental biology, disease pathology, target identification, and drug discovery. Existing RCD detection methods, reliant on biomarkers and fluorescent ...

在病毒研究的领域中，细胞培养是探索病毒奥秘的重要 “阵地”。病毒作为一种特殊的生物，是细胞内的 “寄生客”，在细胞培养过程中，它们有的会引发细胞病变效应（Cytopathic Effects，CPE），有的则 “悄无声息”。这些 CPE 就像是细胞在病毒 “入侵” 后的 “求救信号”，细胞会出现形态上的 ...

Positive samples were inoculated into Marc-145 cells to observe lesions. The Marc-145 cells with cytopathic lesions were identified by indirect immunofluorescence. The whole genome sequences of the ...

We then inoculated the serum containing the XCV genome into Vero 81 cells and obtained one XCV isolate in which the observed cytopathic effect was confirmed on light microscopy (Fig. 1D), the ...

Article Published: May 1999 Emerging cytopathic and antigenic simian immunodeficiency virus variants influence AIDS progression Jason T. Kimata, LaRene Kuller, David B. Anderson, Peter Dailey ...

A rapid decline in T-cell counts and the progression to AIDS is often associated with a switch from CCR5-tropic (R5) HIV-1 to CXCR4–tropic (X4) HIV-1 or R5/X4 HIV-1 variants1,2. Experimental ...

New Virus Discovered In China That Can Affect Brain The virus was first identified in a 61-year-old patient in Jinzhou city in June 2019, who fell ill five days after being bitten by ticks in ...

TCID50是指使50%的细胞发生病变（cytopathic effect，CPE）所需的病毒稀释度。 当我们观察到细胞经过长时间感染后出现病变效应（CPE）时，可以通过显微镜对细胞状态进行观察。

Histology of allergic contact dermatitis would not show viral cytopathic changes and polymerase chain reaction would be negative for VZV. Blaschkitis follows a blaschkoid distribution, rather than ...