idw9 小时
Ablation of HDAC8 accelerates the regeneration of neurons and the recovery of the sensory ...
N. Hertzog et al., Hypoxia-induced conversion of sensory Schwann cells into repair cells is regulated by HDAC8, Nature Communications, 9 January 2025, DOI: 10.1038/s41467-025-55835-9 ...
BioWorld3 天
Potential first-in-class FEM1B-recruiting histone deacetylase degraders divulged
Targeted protein degradation (TPD) is an alternative to conventional protein inhibition that is gaining attention due to advantages such as ensuring complete elimination of the target protein, reduced ...