The eukaryotic translation initiation factor 4E (eIF4E) controls gene expression through its effects on mRNA export and cap‐dependent translation, both of which contribute to its oncogenic potential.

Among other functions, mTOR phosphorylates proteins involved in translation regulation including S6K and 4E-BP1 (eukaryotic translation initiation factor 4E (eIF4E)-binding protein 1). This mTOR ...

Our MD simulation is supported by available data showing that binding of CYFIP1 to eIF4E and binding to the WRC are mutually exclusive and that there is fluorescence resonance energy transfer between ...