Researchers compared how three antioxidants affected gray hair outcomes in mice: hesperetin, diosmetin, and luteolin, and found that one helped mitigate hair graying.

肺动脉高压（PAH）是一种以肺血管重构和肺动脉压力升高为特征的恶性心血管疾病，严重威胁患者生命健康。PASMC过度增殖是导致肺血管重构的关键环节。内皮素-1（ET-1）与ETAR结合在PASMC增殖中发挥重要作用，而ET-1与ETAR结合异常是PAH ...

Hair graying is often seen as a visible sign of aging. Around the world, people search for ways to slow or prevent this process. Despite the demand, few scientifically proven treatments exist. However ...

Sovateltide is a synthetic analog of ET-1 and has very high selectivity for ET-B receptors, which are in high concentration in the CNS. Sovateltide induces ET-B receptor-mediated signaling to produce ...

Background: Although major advances have been made in the pathogenesis and management of pulmonary arterial hypertension (PAH), the endothelin system is still considered to play a vital role in the ...

Despite modern therapy, pulmonary arterial hypertension (PAH) remains a fatal condition. PAH is characterized by construction and remodelling of pulmonary arteries leading to increased pulmonary ...

Medically reviewed by Lindsay Cook, PharmD Pulmonary hypertension (PH) can be challenging for healthcare professionals to ...