导读胆管癌（Cholangiocarcinoma，CCA）是起源于胆道的高致死性恶性肿瘤，5 年总体生存率仅 7%-20%，并且其发病率在全球范围内持续上升。多数患者确诊时已为晚期，无法接受根治性手术，且免疫检查点阻断（Immune ...

Fibroblasts are an important component of the tumour microenvironment. They become activated in tumours, as they do in healing wounds. Here, their roles in tumour initiation, progression and ...

BACKGROUND: Direct reprogramming of fibroblasts to cardiomyocytes is a potentially curative strategy for ischemic heart ...

Researchers in Japan have successfully generated lung cells similar to alveolar epithelial type 2 (AT2) cells from mouse ...

This new article publication from Acta Pharmaceutica Sinica B , discusses how SRSF7 promotes pulmonary fibrosis through regulating PKM alternative splicing in lung fibroblasts. Idiopathic pulmonary ...

The Advanced Wound Care Summit is an ideal forum to showcase how FibroBiologics is pioneering the next generation of wound healing through our fibroblast-based technology," said Mr. O’Heeron. "Our ...

A recent study showed that the differentiation of fibroblasts in the sublining of the synovium of the rheumatoid joint capsule is influenced by the vascular endothelium and implicates the Notch3 ...

Pancreatic cancer is one of the most lethal cancers, with only about 12% of patients surviving five years after diagnosis. A ...

The fibroblasts were directly converted into iPULs (induced pulmonary epithelial-like cells)—functionally akin to native AT2 ...

Volar injections made thigh skin thicker. This therapy could potentially help prevent pressure-induced skin damage in patients using prosthetics.

Fibroblasts are the main connective tissue cells present in the body. As well as being present as fibroblasts, these cells exist in an alternative state, as fibrocytes.